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Company Name: |
Onecoup Lifescience |
| Contact Person: |
Mr.Simon Li |
| City: |
Deyang |
| Country: |
China
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| Local Time: |
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| E-mail: |
Premium
Membership Required (Join Free Today) |
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| Introduction: |
Onecoup Lifescience is a biotechnology business located in Sichuan, China. It specializes in the High-Throughput Screening and optimization technology of recombinant protein renaturation and purification, in developing new strong/
controlled release/target anticancer medicines, which help to control and cure diseases.
The main products are: recombinant human interferon-alpha 2a, pegylated recombinant human interferon-alpha 2a, recombinant human interferon-alpha 2b; pegylated recombinant human interferon-alpha 2b; Recombinant Human Epidermal Growth Factor; Recombinant Human Granulocyte Colony Stimulating Factor; Recombinant Human Human Superoxide Dismutase; recombinant human plasminogen activator, recombinant human Tumoernecrosisfactor.
Onecoup Lifescience also supplies active ingredients derived from snake venom, earthworms, snails and leeches for applications in pharmaceutical and lab research, which include lumbrokinase, snailase, hirudin, nerve growth factor and neurotoxin,
Onecoup has setup tight relationship with the other research labs nationally regarding the latest technology update. They always try to optimize the current materials to develop other better products; new products can be developed and produced on the basis of customers’ requirements.
We are expecting more products and further service recognized and accepted by more of you. |
| Business Type: |
Exporter, Manufacturer, Service |
| Areas of
Interest: |
1. Health & Beauty/Beauty
2. Health & Beauty/Cosmetics
3. Health & Beauty/Medical
4. Health & Beauty/Pharmaceuticals
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Offers
From This Member (6) |
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[Sell] Keratinocyte growth factor |
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Keratinocyte growth factor (KGF) is a potent and specific mitogen for different types of epithelial cells, and it can protect these cells from various insults, which is white lyophilized powder with molecule weight of 19.3KDa, water soluble. Currently there are families of KGF-1 and KGF-2.
KGF is used in skin care products to thicken and repair epidermis layer to smooth wrinkles; repair skin corneal layer to defer the moisture loss of skin; repair wounded epidermis corneal layer to lower the skin sensitivity.
KGF regulates skin cell metabolism based on its complex message transfer network. The physiological functions include:
KGF only acts on epithelial cells instead of fibroblasts and epithelial cells, which specifically stimulates the growth, division and transplant of skin epithelial cells by the combination with the relevant receptor(KGFR) of epithelium membrane.
KGF can stimulate the growth of mature human horn cells; protect radiation and bad motivation from outside, which is anti-inflammatory as well.
KGF lyophilized powder is used as a single product together with dissolution medium; also added to creams and aqua as a function ingredient.
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[Sell] Angiogenin |
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Angiogenin (ANG) is a small polypeptide that is implicated in angiogenesis (formation of new blood vessels) in tumor growth, which is white lyophilized powder with molecule weight of 13.5KDa, water soluble. Currently there are families of ANG1, ANG2, ANG3 and ANG4.
Under specific circumstance, ANG combines with Tie2 to stimulate the formation, reformation and maturation of blood vessels, and keep the completeness of blood vessels and adjust blood vessel function. As the metabolism of all the organs and tissues needs blood circulation to transfer oxygen and nourishment, ANG is important for the body to run normally.
ANG restrains melanocyte secretion of melanocyte stimulating hormone to whiten skin. Meanwhile it stimulate the collagen protein and elastin secretion from melanocyte stimulating hormone, fibroblast, keratinocyte and epidermis cells to defer skin aging and enhance skin elasticity.
ANG lyophilized powder is used as a single product together with dissolution medium; also added to creams and aqua as a function ingredient.
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| » Health & Beauty/Cosmetics |
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[Sell] Recombinant human fibroblast growth factor |
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Recombinant human fibroblast growth factors, or FGFs, are a family of growth factors involved in wound healing and embryonic development, which is white lyophilized powder with molecular weight of 16KDa, which is water soluble, can be kept under room temperature.
Application:
FGF powder can be used as a single product together with dissolution medium; be used in skin care products (creams, aqua, etc) as function ingredient; It is applied in the treatment of chronic wound surface (including chronic granulation wound, ulcer, bedsore, etc), fresh wound surface (including trauma, surgery would, etc) and burn wound surface (including Superficial 2nd Degree wound surface, deep 2nd degree would surface, granulation wound surface, etc).
FGF stimulates the division of different kinds of cells, which also combine into cell specific membrane receptors close to the wound; it shortens the healing time of wounds, repair wounded tissue, reduce scar contraction and skin malformation; and keep skin younger.
FGF is effective to nerve growth and nutrition of in vitro grown neurons, which stimulates the survival and growth of central and peripheral neurons, including cortex, aiBpocampus, striatum, diaphragm, hypothalamus, spinal cord, ganglia ciliare, retinal ganglial cells. Additionally FGF stimulates the division of neuroglia cells and participates in the formation of new blood vessels.
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| » Health & Beauty/Cosmetics |
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[Sell] Recombinant human epidermal growth factor (rhEGF) |
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Brief Introduction
Recombinant human epidermal growth factor (EGF) is a micro molecule peptide with the relative molecular weight of 6.2 KDa, containing 53 amino acid residues. It is a highly efficient cell division factor. The amino acid sequence is Asn-Ser-Asp-Ser-Glu_cys_Pro-Leu-Ser-His-Asp-Gly-Tyr-Cys-Leu. The components include recombinant human epidermal growth factor lyophilized powder and protective agent.
Functions:
The bioactivity features of EGF include effectiveness to the growth and proliferation of skin, cornea, tracheal epithelium tissue in vivo, epithelial cells in human and animals, the healing process of epidermis damage on skin, cornea, etc; controlling the excretion of gastric acid and improving the biosynthesis of protein, RNA, DNA as well as metabolic activity in epidermal cells.
The further skin care actions are helpful to the nutrition absorption of epidermal cells, cell metabolism, division and proliferation; and promotion of the biosynthesis of hyaluronic acid and glycoprotein; improving cell regeneration and tissue plerosis. EGF also has the function of accelerating skin and mucous membrane wound recovery, reducing scar contracture and skin dysmorphosis. Sunscreen effect is another feature of EGF which help cell proliferating, the rebirth of cells damaged by ultraviolet ray and as to reduce pigment cells.
Application:
EGF is applied in curing burn, scald, operational and mechanical injury, skin ulcers, laser cosmetology. Meanwhile EGF is also used in the field of skin care safely and economically.
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| » Health & Beauty/Cosmetics |
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[Sell] Hyaluronic acid |
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Hyaluronic acid (abbreviated as HA, also called sodium hyaluronate) is a straight chain macromolecular mucopolysaccharide composed of repeat disaccharide units of glucuronicacid and N-acetylglucosamine, which exists in the connective tissues of human and animals, including extra cellular space of human and animal tissues, vitreums, umbilical cords, skin joints synovia and cockscomb. Its molecular weight ranges from several ten thousand to several million. Its solution has extraordinary quality of keeping moisture, high viscoelasticity and lubricity. The applications are cosmetics, pharmacy and health and beauty food.
Cosmetic grade HA　
HA is also called Natural Moisturizing Factor (NMF) due to its outstanding moisture keeping feature. It is the best component used in cosmetics for moisture keeping in the nature.
Macromolecular HA helps form an air permeable thin layer and keep the skin smooth and moist, and protect the skin from bacteria, dust and ultraviolet ray, while micromolecule HA penetrates into corium, and slightly enlarge blood capillaries, speed blood circulation, improve intermediary metabolism and nourishment absorbing ability of skin, eliminate wrinkles, increase skin\'s elasticity and postpone aging. HA can also further hyperplasia of epidermis cells, clean oxygen free radicals, prevent and cure skin breach. Its solution has high viscosity thickening water phase. Creams made of HA by emulsifying with oil are emulsification stable, equal and fine.
Meanwhile HA is compatible in different cosmetics such as creams, lotions. cosmetic water, essence, milk for face washing, liquid for bath, agents for hair washing and protection，mousse, lip stick. The dosage about 0.05%-0.5%
Medical grade HA
HA keeps moisture, maintain intercellular space, regulate osmotic pressure, moisturize and help cure cells. The carboxyl and hydroxyl in HA molecules come into being intramolecular and intermolecular hydrogen bonds, which can collect moisture 400 times itself. High concentrate HA solution has high viscoelasticity due to its intermolecular three grade reticular formation. As main part of intercellular substance, HA regulates the exchange of intracellular and intercellular electrolytes, filters physical and molecule information. Macromolecule HA restrain the transfer, proliferation and differentiation of cells, however micromolecule HA is helpful to those actions.
Based on the above features, HA is applied in surgeries of eyes, osteoarthritis , and rheumatoidarthritis. Also it is used in eye drops and surgery recovery. With the development of pharmaceutical technology, hyaluronic acid will be used in more applications.
Food grade HA
With low concentration of HA, the skin becomes coarse and wrinkle, which also leads to arthritis, arteriosclerosis, plus disorder and brain atrophy, that is premature ageing. Oral HA solves these symptoms and keep human body young and full of energy.
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| » Health & Beauty/Beauty |
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[Sell] Metallothionein |
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Brief Introduction:
It is light yellow or white lyophilized powder, a particular protein (also called bioactive peptide) with low molecular weight and high sulfhydryl content, which attaches metallic ions. The purity ranges from 60% to 95%.
1. Low molecular weight: usually 6000-7000 Dalton, with 60-63 amino acid residues.
2. High metal content: each molecular protein attaches 7 divalent metail ions, or 18 univalent metal ions.
3. Particular amino acids: non-aromatic amino acids and histidines, Cys residues (approximately 23-33%), no disulfide bond.
4. Characteristic amino acid sequence: Cys residues are still important in amino acid sequence; all the Cys residues exist in reduced state, which attach metal ions by thioester bonds.
Function:
Science experiments and clinical results show: metallothionein is very effective in resisting ionizing radiation and ultraviolet irradiation; releasing metal toxins; treatment of digestive tract ulcer, myocardial infarction, Inflammations, antianaphylaxis and cancers; skin care; and ease the harm of smoking and environment pollution.
Application:
Metallothionein is widely used in cosmetics, health care products and pharmaceuticals as raw material, 95% purity can be used for injection purpose and professional research and development.
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